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Vitamin D

This section will help you understand the importance of Vitamin D, the risks involved if you are deficient of this vitamin, as well as the risks of toxic effects when taken in an excess amount. The sources of Vitamin D, and how the body utilizes Vitamin D are also discussed.

Vitamin D is a unique compound, in that the body can make it with the help of sunlight. Like Vitamin A, Vitamin D is also important in bone formation. This is because, while Vitamin A works to help in remodeling the bones, Vitamin D on the other hand, helps to mineralize (harden) the bones. In a team effort or collaborative approach, Vitamin D works with Vitamin A, Vitamin C, Calcium, Phosphorous, Magnesium, Flouride, and certain hormones in bone formation. Vitamin D also interacts with other nutrients, such as Pantothenic acid which is essential in its synthesis. Vitamin D is a fat-soluble vitamin in that it requires at least 10% of dietary fat for the body to adequately absorb it.

Vitamin D's specific task is to make sure that Calcium and Phosphorus (the two minerals responsible in completing the process of bone formation), are available in the blood. Along with other hormones, Vitamin D tightly controls the Calcium concentration in the blood and body fluids. As soon as Calcium concentration in the blood reaches its highest peak, Vitamin D directs Calcium to be deposited into the bones. In contrast, when Calcium levels get too low, Vitamin D will work to help correct the problem by enhancing Calcium absorption in the intestine, releasing Calcium from the bone, and reducing Calcium excretion through the kidneys, to normalize blood Calcium levels.

Food does not directly affect Calcium concentration in the blood. It is the regulatory control system that directly affects blood Calcium levels. For example, when your blood Calcium level is too low, it results in a condition called "Calcium Tetany". This condition is manifested by uncontrolled muscle tissue contraction due to the changes in the nerve cell stimulation. The reported possible cause of this is due to a lack of Vitamin D, or problems in the regulatory system in which Vitamin D is a part of. It is however, noteworthy that prolonged inadequate intake of Calcium can lead to a decreased amount of bone Calcium reserves. Because the blood thrives to maintain its Calcium levels, dietary intake of Calcium and Vitamin D is very important to keep the bones from giving up their reserves, thus preventing the bones from becoming fragile and brittle.

Vitamin D was originally thought to be a hormone rather than a vitamin. This is because Vitamin D works just like a hormone. Hormones are made by one body organ to influence another. Vitamin D precursor is made by the liver which is then released into the blood and circulated to the skin. Once this compound in the skin is exposed to the ultraviolet rays of the sun, it goes back into the blood stream. In the blood stream, it goes through several conversion steps in which the liver and kidneys work simultaneously to produce a final product - active Vitamin D. Active Vitamin D then works to promote the making of specific proteins and helping protein work on their specific tasks. This is why, if a person has a kidney or liver problem, bones are also affected and ultimately deteriorate.

The Essential Guide to Vitamins and Minerals by Elizabeth Somer

A single-volume, heavily researched reference covers such areas as the role of each vitamin and mineral, deficiency symptoms, vitamin fallacies, the role of vitamins in disease, antioxidants, and overall health improvement. More...

Functions

Deficiencies

Vitamin D deficiency decreases the absorption of Calcium, which can lead to low levels of Calcium in the blood, thus resulting in brittled bones. The table below lists other Vitamin D deficiencies.

Disease Area Affected Main Effects
Rickets Bones Faulty calcification, resulting in misshapen bones (bowing of legs) and retarded growth. Enlargement of ends of long bones (knees, wrists). Deformities of ribs (bowed, with beads or knobs). Delayed closing of fontannel, resulting in rapid enlargement of head.
  Ears Hearing loss due to porous Cochlea (small snail-shaped bone in the inner ear) which diminishes normal nerve transmission.
  Blood Decreased Calcium and/or Phosphorus levels
  Teeth Slow eruption; teeth not well-formed; tendency to decay.
  Muscles Lax muscles resulting in protrusion of abdomen; muscle spasms.
  Excretory System Increased Calcium in stools; decreased Calcium in urine.
  Glandular System Abnormally high secretion of Parathyroid hormone.
Osteomalacia Bones Softening effect; deformities of limbs, spine, thorax, and pelvis; demineralization; pain in pelvis, lower back, and legs; bone fractures.
  Blood Decreased Calcium and/or Phosphorus; increased Alkaline Phosphatase.
  Muscles Involuntary twitching; muscle Spasms.

 

Toxicity

An excess of Vitamin D increases the absorption of Calcium which leads to high levels of Calcium in the blood. This causes Calcium to precipitate in the soft tissues and produce Calcium stones. Excess Calcium levels also cause calcification or hardening of the blood vessels, thus endangering the arteries of the heart and lungs which may ultimately results in death.

Disease Area Affected Main Effects
Hyper-Vitaminosis D Bones Increased Calcium withdrawal
  Blood Increased Calcium and Phosphorus concentration
  Nervous System Loss of appetite; headache; weakness; Excessive thirst; irritability.
  GI Tract Constipation
  Excretory System Increased excretion of Calcium in Urine, kidney stones; irreversible kidney damage.
  Tissues Calcification of soft tissues (blood vessels, kidneys, heart, lungs, tissues around joints), and death.

 

The Recommended Dietary Allowances (RDAs)

The safe RDA of Vitamin D for growing children is 400 IU (10 micrograms), whereas, adults need around 200 IU (5 micrograms).

  International Units (IU) Micrograms (mcg)
Infants 0-0.5 year 300 7.5
Infants, Children, & Young Adults 0.5 - 24 years 400 10
Adults 25 + 200 5
Pregnant & Lactating 400 10

 

Food Sources

There are other factors that influence the synthesis of Vitamin D via sunlight exposure. The amount of time for sunlight exposure and the type of climate are among them. Darker-skinned people have Melanin (skin pigment) which blocks the sunlight and reduces the body's ability to synthesize Vitamin D. Therefore, they require longer exposure to sunlight. Cloudy-wintery climate lessens sun rays which limits sun exposure. It is important however, to know that over exposure to ultraviolet rays can be hazardous to the body because of its link to skin cancer. An early morning sunlight exposure (sunrise to 11:00 a.m.), or late afternoon (3:00 p.m. to sunset) is believed to be reasonably safe.

There are two ways that you can obtain Vitamin D to meet your body's needs. First, by exposing your skin to sunlight so the body can synthesize it. Second, by eating foods that have preformed Vitamin D, which mainly comes from fish and other animal sources. A plant source of Vitamin D called "ergosterol" is thought to produce active Vitamin D, however, Vitamin D from an animal source is still considered to be the most reliable.

Vitamin D Content of Selected Foods
Food Amount Vitamin D (IU)
Sardines, canned 3 1/2 ounces 1150 - 1570
Makerel, fresh 3 1/2 ounces 1100
Herring, fresh 3 1/2 ounces 315
Salmon, fresh 3 1/2 ounces 154 - 550
Shrimp 3 1/2 ounces 150
Milk, fortified 1 cup 100
Egg yolk 1 average 25
Liver, beef 3 1/2 ounces 9 - 42
Cheese 1 ounce 3 - 4
Butter 1 pat 1.8

 

-- Ofelia B. Mutia, M.S.,R.D.,L.D.

Resources and Acknowledgments

  1. Understanding Normal & Clinical Nutrition by Whitney, Cataldo & Rolfes
  2. The Essential Guide to Vitamins and Minerals by Elizabeth Somer, M.A.,R.D.
  3. Nutrition Concepts & Controversies by Hamilton, Whitney & Sizer
  4. Advanced Nutrition and Human Metabolism by James L. Groff, Sareen S. Gropper
  5. Bowes & Church's Food Values of Portions Commonly Used by Jean A.T. Pennington, Ph.D., Anna De Planter Bowes, Helen N. Church
  6. Essentials of Nutrition and Diet Therapy by Sue Rodwell Williams
  7. ConsumerLab.com - independent tests of herbal, vitamin, and mineral supplements


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Saturday, September 1, 2001